How proteins fold over themselves has a lot to do with how they work. Envisioning such folds is a hugely complex problem for computers that human brains with eyeballs attached happen sometimes to be able to do better. The FoldIt game supplies humans with protein models and asks them to fold ‘em.
According to a post by Alan Boyle at MSNBC.com: “Video-game players have solved a molecular puzzle that stumped scientists for years, and those scientists say the accomplishment could point the way to crowdsourced cures for AIDS and other diseases.” The post is about an article in Nature Structural & Molecular Biology by Firas Khatib et al.
Way to go, human brains!
(I talk about FoldIt in Too Big to Know, which has now gone to press. Ohhh, irrevocably ink-stained paper!)